Dr.sathya balasubramanyam

MD DNB MRCOG (UK) FNB(Reprod med)

An infertility treatment procedure that is widely used and often abused in treating subfertility, Intrauterine Insemination is popularly referred to as IUI. The procedure mainly involves the injection of extracted and processed sperm, directly into the womb or uterine cavity of the women. This procedure is performed after assessing the period of ovulation in the women and done just before or during ovulation.

Intra Uterine Insemination

 The goal of the procedure is to ensure fertilisation by increasing the number of sperms that reaches the fallopian tubes. It offers a head start to the sperm although the fertilisation should occur naturally. The procedure is considered to be less invasive than the other procedures involved in ART (Artificial Reproduction Techniques).

Scope of IUI treatment

IUI is usually preferred in many cases of subfertility in both men and women. They are used in following cases

  • Mild endometriosis

  • Failed anovulation

  • In cases of male erectile dysfunction

  • For donor insemination due to severe teratozoospermia, azoospermia and genetic disorders

The procedure is performed only after checking the fallopian tube patency of the women as IUI is not recommended in women with severe fallopian tube disorders. They are also not preferred in women with severe endometriosis or pelvic infection history.

IUI Treatment Procedure

IUI treatment procedure has an average success rate of about 15%, with lower success when male subfertility factors are involved. The details of the treatment, its success rate and other associated details are discussed with the couple before the start of the treatment. We do not believe in giving unrealistic expectations to our patients.

The procedure of IUI can be performed either through natural cycles or in stimulated cycles. The stimulated cycles of IUI are initiated after checking the levels of LH to prevent it from interfering with the follicular development. In the case of high levels of LH, sometimes antagonists or GnRH are to be used. Follicular tracking is mandatorily performed while using gonadotrophins as these are associated with multi-follicular development.

IUI is uncontrolled when it comes to deciding the number of eggs that is fertilised and the number of embryos that get implanted in the uterus following this procedure of stimulated IUI with gonadotrophins. Hence the risk of multiple births is high in these cases of IUI. If the risks are high, the patients can opt for IVF, which reduces the risk considerably.

The procedure of IUI is not simple. It is done after cleaning the cervical mucus with saline or culture media as part of a precautionary measure for a safe procedure. Processed sperm in about 0.5ml measure is injected into the uterine cavity with the help of a catheter. Maximum care is taken to minimise the discomfort associated with the procedure.

If the woman fails to conceive successfully even after completing 6 cycles of the procedure, other treatment procedures such as IVF or ICSI are done. They are known to have higher success rate. Although the cost of IVF is higher than IUI, the higher efficiency of the treatment nullifies the effect.

 

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DR.SATHYA BALASUBRAMANYAM

Dr. Sathya Balasubramanyam

MD DNB MRCOG (UK)
FNB(Reprod med)

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CLOUD NINE HOSPITAL

Clinical Director Fertility

SEETHAPATHY CLINIC AND HOSPITAL

Consultant Reproductive Medicine

SUNDARAM MEDICAL FOUNDATION

Consultant Reproductive Medicine

VIJAYA HOSPITAL

Consultant Reproductive Medicine


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